TY - JOUR
T1 - Patient-Centric Pharmaceutical Technologies: Dosage Design, Adherence Logic, and Real-World Use Systems
AU - Maria Gonzalez
AU - Javier Ruiz
AU - Lucia Torres
AU - Elena Ruiz
JF - EAMD 3
Y1 - 0
VL - 0
IS - 0
SP - 174
N2 - Pharmaceutical development is increasingly moving beyond the traditional emphasis on drug substance performance to include the full experience of medicine use. This shift reflects the recognition that therapeutic value is shaped not only by pharmacology, but also by whether patients can understand, accept, handle, administer, and continue using a product in everyday life. Despite major advances in dosage form engineering, digital health tools, adherence monitoring, and personalised pharmaceutical manufacturing, many innovations remain disconnected from the practical contexts in which medicines are used. A dosage form may be technically sophisticated but still fail if it is difficult to swallow, unattractive to children, burdensome for older adults, incompatible with daily routines, or unsupported by feedback systems that encourage continued use. This narrative review integrates three domains that are often discussed separately: dosage design, adherence logic, and real-world use systems. It argues that patient-centric pharmaceutical technologies should be understood as integrated use systems rather than isolated product features. The central question is how pharmaceutical technologies can be designed to support not only drug delivery, but also patient acceptance, behavioural continuity, and implementation in real healthcare settings. The review concludes that patient-centricity should be treated as a foundational development logic rather than a late-stage product attribute. Future pharmaceutical technologies will require early patient involvement, scalable manufacturing pathways, human factors validation, digital support systems, and regulatory strategies that define success according to real-world usability and patient-defined outcomes.
UR - https://pubsys.eshragh.co/n258922099
ER -